DNA Sequencing in Adults With Acute Myeloid Leukemia to Detect Residual Disease Prior to Hematopoietic Cell Transplant—Reply

In Reply We thank Dr Khaire and colleagues for their interest in our study, and for their agreement that the study provides strong evidence that the detection of persistent FLT3-ITD or NPM1 variants in the blood samples of adults during first remission from AML prior to allogeneic transplant is associated with increased posttransplant relapse and death, compared with those testing negative.