Batten disease is a group of fatal, inherited lysosomal storage disorders that predominantly affect children. The most prevalent form is CLN3 disease, for which there is no cure. Retinal degeneration and resulting vision loss is one of the symptoms.
Electronic filters are essential to the inner workings of our phones and other wireless devices. They eliminate or enhance specific input signals to achieve the desired output signals. They are essential, but take up space on the chips that researchers are on a constant quest to make smaller. A new study demonstrates the successful integration of the individual elements that make up electronic filters onto a single component, significantly reducing the amount of space taken up by the device.
Young adults and adolescents who are prescribed opioids for the first time may be at a slightly greater risk of developing a substance-related problem later in life, according to a new study co-authored by Indiana University researchers. However, the risk may not be as high as previously thought.
Researchers from Columbia Engineering and the University of Pittsburgh have developed a sensitive and specific early warning system for predicting necrotizing enterocolitis (NEC) in premature infants before the life-threatening intestinal disease occurs. The prototype predicts NEC accurately and early, using stool microbiome features combined with clinical and demographic information. 'The lessons we've learned from our new technique could well translate to other genetic or proteomic datasets and... Читать дальше...
The mechanisms that make organisms locally fit and those responsible for change are distinct and occur sequentially in evolution.
A new longitudinal study sought to learn more about the impact of school resource officers (SROs). The study found that schools that increased staffing levels of SROs were more likely to record increases in crimes and to exclude students from school in response to those crimes than schools without increases in SRO staffing levels; moreover, the increases in crimes and exclusions recorded persisted for up to 20 months.
If voters gravitate toward the center of the political spectrum, why are the parties drifting farther apart? A new model reveals a mechanism for increased polarization in US politics, guided by the idea of 'satisficing'-- that people will settle for a candidate who is 'good enough.'
Cervical cancer kills more than 300,000 middle-aged women a year, and 19 of the 20 nations with the highest death rates are sub-Saharan countries. Now an international team, including Akinyemi I. Ojesina, M.D., Ph.D., University of Alabama at Birmingham, has published the first comprehensive genomic study of cervical cancers in sub-Saharan Africa, with a focus on tumors from 212 Ugandan patients with cervical cancer.
1. Initial weeks of pandemic saw a swift increase in virtual visits, sharp decrease in in-person visits at the VA ; 2. Researchers report cases of myasthenia gravis associated with COVID-19 infection.
On Aug. 9, 2020 NASA's Aqua satellite imaged the Apple Fire near Big Bear Lake in California using its false-color bands in order to be able to distinguish burn scars from the surrounding area more easily.
Remembering Brent Scowcroft
Donald Trump’s policies for marginalized Americans closely resemble the recommendations made in a new book—though its authors don’t seem to recognize it.
Letitia James’s proposal to dissolve the NRA, a nonprofit organization, is alarming.
(University of Notre Dame) Researchers at the University of Notre Dame are developing a new technique using artificial intelligence (AI) that would improve CT screening to more quickly identify patients with the coronavirus.
(Rice University) The Rice University-based Center for Theoretical Biological Physics has won a five-year extension from the National Science Foundation to pursue its investigation of mysteries at the intersection of biology and physics.
(University of California - Davis) The National Institutes of Health has awarded a grant of $1.2 million to the Mouse Biology Program at UC Davis to create mice that are susceptible to the COVID-19 virus, and to distribute them to researchers. The goal is to create mice that can be used to reproduce human COVID-19 disease.
(Lehigh University) Results of a new study by Lehigh University's Jill McDermott and colleagues contradict the assumption that hydrogen depletions at the seafloor are caused by microbiological communities. They found that these shifts in chemistry are driven by non-biological processes that remove energy before microbial communities at the shallow seafloor gain access to it. The results were published online today in the Proceedings of the National Academy of Sciences.
(National Centre for Biological Sciences) We have almost no idea how air pollution affects other organisms who breathe the same air as we do. In some of the first research in the world to try to address the physiological and molecular impacts of air pollution on our wild plants and animals, scientists from the Bangalore Life Science Cluster show that air pollution could be devastating for organisms we rely on most for our own survival - like the honey bee.
In a study published today in the Journal of the American College of Cardiology of more than 5,000 acute coronary syndromes (ACS) patients, 71.8% were considered malnourished by at least one nutrition screening test, and worsening malnutrition status was associated with higher mortality and major adverse cardiovascular events (MACE), such as another heart attack or stroke.
What is the role and molecular basis of electrical signaling in higher plants? This can now be investigated non-invasively for the first time. The new method has been published in the journal PNAS.
Social protection programs can facilitate progress towards the Sustainable Development Goals (SDGs) but can also create trade-offs across divergent social and environmental goals that can undermine their effectiveness, say the authors of new research published in the journal PNAS. This is one of the largest studies on the sustainability implications of social protection, funded by the Grantham Centre for Sustainable Futures at The University of Sheffield.
One way to cut back on deforestation in the Amazon rainforest - and help in the global fight against climate change - is to grant more of Brazil's indigenous communities full property rights to tribal lands. This policy focus is suggested by the findings of a new study in PNAS.
A study of older mice with type 2 diabetes has yielded highly promising results for researchers investigating potential new vaccines for tuberculosis (TB). A team of researchers from Australia, Bangladesh and France investigated a potential vaccine, BCG::RD1, and found it highly protective when administered directly into the lungs of diabetic mice, which were then exposed to TB.
Although macrophages (cells involved in the detection and destruction of bacteria and other harmful organisms as well as dead cells) are classified as immune cells functioning in the activation and resolution of tissue inflammation, it is now clear that they are critically involved in a variety of disease processes, such as chronic inflammatory diseases, tumor growth and metastasis and tissue fibrosis.
