A tale of 2 gasses, 1 regulator, and cholesterol homeostasis
by Nicole M. Fenton, Andrew J. Brown
There is a burgeoning appreciation for the wide-ranging effects of carbon dioxide on transcriptional regulation and metabolism. Here, Bolshette and colleagues provide the first link between carbon dioxide and the master transcriptional regulator of cholesterol homeostasis. There is a growing appreciation of the wide-ranging effects of carbon dioxide on transcriptional regulation and metabolism. This Primer explores a study that provides the first link between carbon dioxide and the master transcriptional regulator of cholesterol homeostasis.