Methamphetamine (meth) abuse is a major health concern. Understanding how meth interacts with its target proteins is crucial for the development of novel medications to address drug addiction. Previous research into the mechanism of meth's effects has mainly focused on the dopamine system, but recent studies suggest it may also directly bind to the trace amine receptor 1 (TAAR1), which plays a key role in psychostimulant abuse-related behaviors.
