Orthohantaviruses, such as the Puumala virus, are widespread in Europe, causing flu-like illnesses and severe kidney damage in those infected. It is increasingly considered a zoonotic threat. Researchers from the Medical Faculty of the University of Duisburg-Essen and the University Hospital Essen, Germany, have gained new insights into how these viruses alter the internal structure of their host cells. Their findings are published in the Journal of General Virology.