The No. 1 Buckeyes (7-0, 4-0) will take on Purdue (2-6, 0-5) on Nov. 8 at Ross-Ade Stadium and the game will kickoff at 1 p.m. ET. This will be the first time in 20 years Ohio State has a regular season game that kicks off at 1 p.m. ET when the Buckeyes played at Michigan on Nov. 19, 2005.

Nov. 8 will mark the 60th official meeting between Ohio State and the Boilermakers. This game will also be the first to be played after the initial College Football Playoff rankings are revealed on Nov. 4.

But before this contest, each team will play on Saturday in Week 10 as Ohio State hosts Penn State in Columbus at noon and Purdue looks for its first Big Ten win at No. 21 Michigan in Ann Arbor at 7 p.m.

Ohio State has won three straight against Purdue dating back to 2021. The last time the Boilermakers beat the Buckeyes was at home in 2018 with their famous 49-20 upset win. In fact, this is one of the few Big Ten matchups where Ohio State has not utterly dominated this century with Purdue having five wins since 2000.

Remaining 2025 Ohio State football schedule

Nov. 1: Penn State, noon
Nov. 8: at Purdue, 1 p.m.
Nov. 15: UCLA
Nov. 22: Rutgers
Nov. 29: at Michigan, noon

This season's game may not produce an upset as Purdue is struggling through Big Ten play and have lost six straight games. After nonconference wins over Ball State and Southern Illinois to begin the year, the Boilermakers have lost to USC, Notre Dame, Illinois, Minnesota, Northwestern, and Rutgers.

Barring a four-game winning streak to end the year with miraculous wins over No. 21 Michigan, No. 1 Ohio State, Washington, and No. 2 Indiana, Purdue is destined to not play a bowl game for a third successive season.

NBC4's coverage of college football will continue for Week 10 in Lincoln, Nebraska as the Cornhuskers host USC at 7:30 p.m. on Saturday. NBC4 will also show a noon Big Ten game on Saturday from Champaign, Illinois as the Fighting Illini host Rutgers.

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