The vast majority—more than 96%—of people aged 16 years or older in the US had SARS-CoV-2 antibodies by September 2022, including about 48% who had “hybrid immunity,” or immunity derived from both vaccination against and infection with the virus. People who were unvaccinated were more likely to have antibodies from infection compared with people who were vaccinated, according to an analysis of 72 748 blood donors.
