In Reply In response to our recent Review, Dr Wang raises several interesting points regarding the use of prophylaxis against P jirovecii pneumonia in patients with glioma, but conflates 2 different clinical scenarios. The first is P jirovecii pneumonia prophylaxis in the setting of long-term steroid use (>4 weeks), as discussed in our Review. The second scenario is empirical P jirovecii pneumonia prophylaxis in the setting of chemoradiation, which is the scenario addressed in the article cited by Wang.
