In Reply We thank Mr Lu and colleagues for their interest in our recent article. In response to their first comment, it is important to note that body weights in this study were self-reported by participants approximately every 2 years and were not measured at clinic visits. Therefore, the frequency of clinic visits did not dictate the availability of weight data or the ability to assess recent weight change prior to a cancer diagnosis. However, we agree that outside this study, frequency of clinic visits could affect how promptly clinicians are informed of recent weight changes and when cancer-directed evaluations are initiated.