Fat Tissue Can Help Cancer Cells Proliferate, Metastasize
J. Huang et al., Adipocyte p62/SQSTM1 suppresses tumorigenesis through opposite regulations of metabolism in adipose tissue and tumor, Cancer Cell, 33:77084, 2018.Obesity is second only to smoking as the biggest preventable cause of cancer in the US. It's linked not only to cancer incidence, but also to disease progression and outcome. So understanding how fat tissue communicates with tumor cells in vivo has long been a goal for cancer researchers.